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HSP27 inhibitor J2

CAS No. 2133499-85-9

HSP27 inhibitor J2( —— )

Catalog No. M13399 CAS No. 2133499-85-9

HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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2MG	176	In Stock
5MG	295	In Stock
10MG	447	In Stock
25MG	714	In Stock
50MG	1008	In Stock
100MG	1341	In Stock
200MG	Get Quote	In Stock
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Biological Information

Product Name

HSP27 inhibitor J2
Note

Research use only, not for human use.
Brief Description

HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27.
Description

HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27, induces significant abnormal HSP27 dimer formation in cancer cells; enhances cancer cell sensitization with cisplatin, cisplatin-induced lung cancer cell growth inhibition in vitro; significantly inhibits immune cell infiltration in lung tissue, attenuates radiation-induced pulmonary inflammation in mice.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

HSP
Recptor

HSP
Research Area

——
Indication

——

Chemical Information

CAS Number

2133499-85-9
Formula Weight

264.295
Molecular Formula

C13H12O4S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 20 mg/mL (75.67 mM)
SMILES

O=C1C=C(C)OC2=C1C(O)=CC(OCC3SC3)=C2
Chemical Name

5-hydroxy-2-methyl-7-(thiiran-2-ylmethoxy)-4H-chromen-4-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kim JY, et al. Sci Rep. 2018 Mar 8;8(1):4189. 2. Hwang SY, et al. Eur J Med Chem. 2017 Oct 20;139:892-900.

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